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Case Reports
. 2008 Jul;12(3):181-5.

Clear cell ovarian carcinoma following polymyositis diagnosis: a case report and review of the literature

I Kalogiannidis  1 , A Papanikolaou, I Xanthakis, A Makedos, N Prapas
Affiliations
Case Reports

Clear cell ovarian carcinoma following polymyositis diagnosis: a case report and review of the literature

I Kalogiannidis et al. Hippokratia. 2008 Jul.

Abstract

Background: The association of ovarian malignancy with dermatomyositis (DM) is well established from previous reports, while the relationship with polymyositis (PM) is rare.

Case report: We report a case of a 50 years old nulliparous woman who developed clear cell ovarian cancer four years after the PM diagnosis. The patient presented with deep lower abdominal pain and distension. CA-125 was elevated and the preoperative MRI showed pelvic tumor occupying the Douglas pouch. Exploratory laparotomy revealed a gross mass of clear cell ovarian carcinoma.

Conclusion: Physicians must be alert of the possibility of malignancy in patients with a previous diagnosis of polymyositis.

Keywords: dermatomyositis; inflammatory myositis; ovarian cancer; polymyositis.

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Figures

Figure 1.
Figure 1.. Magnetic resonance imaging (MRI) showing ovarian tumor of mixed feature.
Figure 2.
Figure 2.. Histopathological section of the specimen showing the solid part of the tumor.
Figure 3.
Figure 3.. The microscopic (× 400) appearance of the clear cell ovarian carcinoma.
See this image and copyright information in PMC

References

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