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Editorial
. 2008 Oct 7;52(15):1261-2.
doi: 10.1016/j.jacc.2008.07.021.

Lamin A/C gene and the heart: how genetics may impact clinical care

Luisa Mestroni, Matthew R G Taylor
Editorial

Lamin A/C gene and the heart: how genetics may impact clinical care

Luisa Mestroni et al. J Am Coll Cardiol. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest or financial disclosures associated with this work.

Comment on

  • Long-term outcome and risk stratification in dilated cardiolaminopathies.
    Pasotti M, Klersy C, Pilotto A, Marziliano N, Rapezzi C, Serio A, Mannarino S, Gambarin F, Favalli V, Grasso M, Agozzino M, Campana C, Gavazzi A, Febo O, Marini M, Landolina M, Mortara A, Piccolo G, Viganò M, Tavazzi L, Arbustini E. Pasotti M, et al. J Am Coll Cardiol. 2008 Oct 7;52(15):1250-60. doi: 10.1016/j.jacc.2008.06.044. J Am Coll Cardiol. 2008. PMID: 18926329

References

    1. Capell BC, Collins FS. Human laminopathies: nuclei gone genetically awry. Nat Rev Genet. 2006;7:940–52. - PubMed
    1. Rankin J, Edwards JG. The laminopathies: a clinical review. Clin Genet. 2006;70:261–74. - PubMed
    1. Taylor MRG, Fain P, Sinagra G, Robinson M, Robertson AD, Carniel E, Di Lenarda A, Bohlmeyer TJ, Ferguson DA, Brodsky GL, Boucek MM, Lascor J, Moss AC, Li WL, Stetler GL, Muntoni F, Bristow MR, Mestroni L. Natural history of dilated cardiomyopathy due to lamin A/C gene mutations. J Am Coll Cardiol. 2003;41:771–80. - PubMed
    1. Meune C, Van Berlo JH, Anselme F, Bonne G, Pinto YM, Duboc D. Primary prevention of sudden death in patients with lamin A/C gene mutations. N Engl J Med. 2006;354:209–10. - PubMed
    1. Parks SB, Kushner JD, Nauman D, Burgess D, Ludwigsen S, Peterson A, Li D, Jakobs P, Litt M, Porter CB, Rahko PS, Hershberger RE. Lamin A/C mutation analysis in a cohort of 324 unrelated patients with idiopathic or familial dilated cardiomyopathy. Am Heart J. 2008;156:161–9. - PMC - PubMed