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Review
. 2009:60:85-103.
doi: 10.1146/annurev.physchem.58.032806.104445.

Dewetting and hydrophobic interaction in physical and biological systems

Affiliations
Review

Dewetting and hydrophobic interaction in physical and biological systems

Bruce J Berne et al. Annu Rev Phys Chem. 2009.

Abstract

Hydrophobicity manifests itself differently on large and small length scales. This review focuses on large-length-scale hydrophobicity, particularly on dewetting at single hydrophobic surfaces and drying in regions bounded on two or more sides by hydrophobic surfaces. We review applicable theories, simulations, and experiments pertaining to large-scale hydrophobicity in physical and biomolecular systems and clarify some of the critical issues pertaining to this subject. Given space constraints, we cannot review all the significant and interesting work in this active field.

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References

    1. Dobson CM, Sali A, Karplus M. Protein folding: a perspective from theory and experiment. Angrew Chem Int Edit Engl. 1998;37:868–893. - PubMed
    1. Brooks CL, Gruebele M, Onuchic JN, Wolynes PG. Chemical physics of protein folding. Proc Natl Acad Sci U S A. 1998;95:11037. - PMC - PubMed
    1. Dill KA, Chan HS. From levinthal to pathways to funnels. Nature Struc Bio. 1997;4:10–19. - PubMed
    1. Socci ND, Onuchic JN, Wolynes PG. Protein folding mechanisms and the multidimensional folding funnel. Proteins. 1998;32:136. - PubMed
    1. Hummer G, Garde S, Garcia AE, Pratt LR. New perspectives on hydrophobic effects. Chem Phys. 2000;258:349–370.

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