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Review
. 2008 Oct;55(5):1129-46, viii.
doi: 10.1016/j.pcl.2008.07.005.

Autism: definition, neurobiology, screening, diagnosis

Isabelle Rapin  1 , Roberto F Tuchman
Affiliations
Review

Autism: definition, neurobiology, screening, diagnosis

Isabelle Rapin et al. Pediatr Clin North Am. 2008 Oct.

Abstract

Autism (ie, the autism spectrum disorders) is now recognized in 1 in 150 children. This article highlights the definition, neurobiology, screening, and diagnosis of autism. The genetics, immunology, imaging, and neurophysiology of autism are reviewed, with particular emphasis on areas that impact pediatricians. Early recognition of the social deficits that characterize autism is key to maximizing the potential of these children.

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