Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Oct 28:(40):4962-4.
doi: 10.1039/b812901k. Epub 2008 Sep 10.

Identification of an anti-MRSA dihydrofolate reductase inhibitor from a diversity-oriented synthesis

Emma E Wyatt  1 , Warren R J D Galloway, Gemma L Thomas, Martin Welch, Olivier Loiseleur, Alleyn T Plowright, David R Spring
Affiliations

Identification of an anti-MRSA dihydrofolate reductase inhibitor from a diversity-oriented synthesis

Emma E Wyatt et al. Chem Commun (Camb). .

Abstract

The screening of a diversity-oriented synthesis library followed by structure-activity relationship investigations have led to the discovery of an anti-MRSA agent which operates as an inhibitor of Staphylococcus aureus dihydrofolate reductase.

PubMed Disclaimer

Publication types

MeSH terms

Substances

LinkOut - more resources