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. 2008 Oct 28:(40):4974-6.
doi: 10.1039/b810708d. Epub 2008 Sep 12.

One-pot approach for the synthesis of trans-cyclopropyl compounds from aldehydes. Application to the synthesis of GPR40 receptor agonists

Michaël Davi  1 , Hélène Lebel
Affiliations

One-pot approach for the synthesis of trans-cyclopropyl compounds from aldehydes. Application to the synthesis of GPR40 receptor agonists

Michaël Davi et al. Chem Commun (Camb). .

Abstract

A novel multicatalytic one-pot process providing trans-cyclopropyl compounds from corresponding aldehydes has been developed and applied to the synthesis of GPR40 small molecule agonists.

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