Review
doi: 10.1007/s11882-008-0094-7.
Gastric pepsin in middle ear fluid of children with otitis media: clinical implications
Affiliations
- PMID: 18940143
- DOI: 10.1007/s11882-008-0094-7
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Review
Gastric pepsin in middle ear fluid of children with otitis media: clinical implications
Curr Allergy Asthma Rep.
2008 Nov.
Abstract
Gastroesophageal reflux and extraesophageal reflux have been postulated to be involved in the pathogenesis of otitis media. This is supported by recent studies revealing the presence of gastric pepsin in the middle ear space of children with otitis media but not in control patients without otitis media. Reflux's role in otitis media appears to be most pronounced in younger children and those with purulent effusions.
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