Expandable endodermal progenitors: new tools to explore endoderm and its derivatives
- PMID: 18940723
- DOI: 10.1016/j.stem.2008.09.010
Expandable endodermal progenitors: new tools to explore endoderm and its derivatives
Abstract
In the two recent issues of Cell Stem Cell, Rossant and colleagues (Seguin et al., 2008) produced expandable endoderm from hESCs by constitutive expression of Sox transcription factors, while Brickman and associates (Morrison et al., 2008) used a reporter gene strategy to isolate replicating anterior definitive endoderm from mESCs.
Comment on
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Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells.Cell Stem Cell. 2008 Aug 7;3(2):182-95. doi: 10.1016/j.stem.2008.06.018. Cell Stem Cell. 2008. PMID: 18682240
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Anterior definitive endoderm from ESCs reveals a role for FGF signaling.Cell Stem Cell. 2008 Oct 9;3(4):402-15. doi: 10.1016/j.stem.2008.07.021. Cell Stem Cell. 2008. PMID: 18940732
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