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Comparative Study
. 2009 Feb;35(1):51-7.
doi: 10.1016/j.burns.2008.07.018. Epub 2008 Oct 31.

Matriderm versus Integra: a comparative experimental study

Joerg Schneider  1 , Thomas Biedermann, Daniel Widmer, Irene Montano, Martin Meuli, Ernst Reichmann, Clemens Schiestl
Affiliations
Comparative Study

Matriderm versus Integra: a comparative experimental study

Joerg Schneider et al. Burns. 2009 Feb.

Abstract

Aim: To compare engraftment rates and vascularisation in a rat model using either Integra Artificial Skin or Matriderm.

Methods: Matriderm and the dermal part of Integra were compared in a two-step procedure including matrix implantation and subsequent epidermal grafting. Neonatal rat epidermis was used as coverage to test for rapid and complete take.

Results: Efficiency and quality of vascularisation expressed by take rate of epidermis, and thickness of resulting neodermis, were identical for both matrices.

Conclusion: This first comparison of Matriderm with Integra in a rat model revealed no major differences in engraftment rates or vascularisation.

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