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Comparative Study
. 1991 Sep;35(3):159-61.
doi: 10.1099/00222615-35-3-159.

Comparison of a DNA probe assay with culture for the detection of Chlamydia trachomatis

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Comparative Study

Comparison of a DNA probe assay with culture for the detection of Chlamydia trachomatis

M I Lees et al. J Med Microbiol. 1991 Sep.

Abstract

A new DNA probe assay (PACE 2, Gen-probe) was compared with cell culture for the detection of Chlamydia trachomatis in 909 women attending the Royal Women's Hospital, Melbourne, Victoria. The DNA probe assay had a sensitivity of 86.2%, a specificity of 99.9% and a positive predictive value of 96.2% in a population with 3.2% prevalence, indicating that it may be a suitable alternative to culture for the detection of C. trachomatis in specimens from the genital tract.

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