Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 May;23(4):429-35.
doi: 10.1016/j.janxdis.2008.08.008. Epub 2008 Sep 6.

Substance use disorders in an obsessive compulsive disorder clinical sample

Maria C Mancebo  1 , Jon E Grant, Anthony Pinto, Jane L Eisen, Steven A Rasmussen
Affiliations

Substance use disorders in an obsessive compulsive disorder clinical sample

Maria C Mancebo et al. J Anxiety Disord. 2009 May.

Abstract

The prevalence and clinical correlates of substance use disorders (SUDs) were examined in a clinical sample of Obsessive Compulsive Disorder (OCD). As part of their intake interview into an observational study of the course of OCD, 323 participants completed a battery of standardized measures. Twenty-seven percent of the sample met lifetime criteria for a SUD. 70% of participants with comorbid SUDs reported that OCD preceded SUD onset by at least one year. Younger age at OCD onset and presence of Borderline Personality Disorder (BPD) were each associated with increased risk of alcohol use disorders but only BPD was associated with increased risk of drug use disorders. SUDs affect more than one-quarter of individuals who seek treatment for OCD. Individuals with a juvenile-onset of OCD or comorbid BPD may be especially vulnerable to SUDs. Further research is needed to identify risk factors for SUDs and to better understand their impact on OCD course.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Temporal sequence of OCD and SUD onset (n=87)
See this image and copyright information in PMC

References

    1. American Psychiatric Association . Diagnostic and statistical manual of mental disorders. Fourth ed. American Psychiatric Association; Washington, D.C.: 2000.
    1. Cassidy F, Ahearn EP, Carroll BJ. Substance abuse in bipolar disorder. Bipolar Disorders. 2001;3(4):181–188. - PubMed
    1. Cohen P, Chen H, Crawford TN, Brook JS, Gordon K. Personality disorders in early adolescence and the development of later substance use disorders in the general population. Drug and Alcohol Dependence. 2007;88(Suppl 1):S71–84. - PMC - PubMed
    1. Conger JJ. Alcoholism: theory, problem and challenge. II. Reinforcement theory and the dynamics of alcoholism. Quarterly Journal of Studies on Alcohol. 1956;17:296–305. - PubMed
    1. Davis LL, Frazier E, Husain MM, Warden D, Trivedi M, Fava M, et al. Substance use disorder comorbidity in major depressive disorder: a confirmatory analysis of the STAR*D cohort. American Journal of Addictions. 2006;15(4):278–285. - PubMed

Publication types

MeSH terms