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Review
. 2008 Nov;47(5):526-43.
doi: 10.1097/MPG.0b013e318175dda1.

Treatment regimen adherence in pediatric gastroenterology

Kevin A Hommel  1 , Laura M Mackner, Lee A Denson, Wallace V Crandall
Affiliations
Review

Treatment regimen adherence in pediatric gastroenterology

Kevin A Hommel et al. J Pediatr Gastroenterol Nutr. 2008 Nov.

Abstract

Objective: To review and critically evaluate the extant research pertaining to adherence in pediatric gastroenterological diseases, particularly inflammatory bowel disease and celiac disease, and to provide recommendations for future research development.

Materials and methods: A literature search with no date restriction was conducted using PubMed and PsychInfo electronic databases and bibliographies of relevant articles.

Results: Adherence rates in inflammatory bowel disease and celiac disease range considerably from 16% to 62% and 5% to 70%, respectively, across treatments and assessment method; nonadherence frequency was generally not reported. Measures used to assess adherence included self-report, interview, diet record, and bioassay methods, and each measure demonstrated strengths and limitations. Limited evidence suggests that adherence in both disease populations is related to patient and family behavioral factors and that nonadherence is related to poor disease outcome. Treatment outcome research for nonadherence is scant in the current literature.

Conclusions: Future research should focus on refining assessment method, examining adherence and concomitant behavioral factors longitudinally, testing theoretical models of adherence, and developing efficacious treatments for nonadherence.

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Conflict of interest statement

The authors report no conflicts of interest.

References

    1. Rapoff MA. Adherence to Pediatric Medical Regimens. New York: Kluwer Academic; 1999.
    1. Lemanek K. Adherence issues in the medical management of asthma. J Pediatr Psychol. 1990;15:437–458. - PubMed
    1. Sly RM. Mortality from asthma in children, 1979–1984. Ann Allergy. 1988;60:433–443. - PubMed
    1. Berg JS, Dischler J, Wagner DJ, et al. Medication compliance: a health care problem. Ann Pharmacother. 1993;27:S2–1. - PubMed
    1. Rapoff MA, Barnard MU. Compliance with pediatric medical regimens. In: Cramer JA, Spilker B, editors. Patient Compliance in Medical Practice and Clinical Trials. New York: Raven Press; 1991. pp. 73–98.

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