Update on apraxia
- PMID: 18957186
- PMCID: PMC2696397
- DOI: 10.1007/s11910-008-0078-y
Update on apraxia
Abstract
Apraxia is classically defined as difficulty performing learned, skilled gestures. In this review, we describe the range of motor impairments classified as apraxia, focusing on ideomotor limb apraxia. We present several prominent models of praxis to explain the variety of difficulties seen in patients with apraxia. We also discuss the large-scale frontal-parietal-basal ganglia network thought to underlie praxis. In this context, we highlight the common occurrence of limb apraxia in corticobasal degeneration, a neurodegenerative condition characterized by frontal, parietal, and basal ganglia disease.
References
-
- Heilman KM, Rothi LJG. Apraxia. In: Heilman KM, Valenstein E, editors. Clinical Neuropsychology. New York: Oxford University Press; 2003. pp. 215–235.
-
- Leiguarda RC, Marsden CD. Limb apraxias: higher-order disorders of sensorimotor integration. Brain. 2000;123(Pt 5):860–879. - PubMed
-
- Mahapatra RK, Edwards MJ, Schott JM, Bhatia KP. Corticobasal degeneration. Lancet Neurol. 2004;3:736–743. - PubMed
-
-
Murray R, Neumann M, Forman MS, et al. Cognitive and motor assessment in autopsy-proven corticobasal degeneration. Neurology. 2007;68:1274–1283. This article describes the cognitive and motor features of CBD. Its major strengths include use of autopsy-proven cases and a fine-grained analysis of cognitive function. The authors show that CBD patients have a specific profile of cognitive impairment related to the neuroanatomic distribution of disease.
-
-
- Leiguarda R. Limb apraxia: cortical or subcortical. Neuroimage. 2001;14:S137–S141. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources