Gene regulation: a tale of germline mRNA tails
- PMID: 18957237
- DOI: 10.1016/j.cub.2008.08.001
Gene regulation: a tale of germline mRNA tails
Abstract
Gene regulation often plays by different rules in the germline compared to the soma. In Caenorhabditis elegans, the spatial and temporal expression of germline genes is controlled post-transcriptionally via the 3' UTR rather than transcriptionally via the promoter.
Comment on
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3' UTRs are the primary regulators of gene expression in the C. elegans germline.Curr Biol. 2008 Oct 14;18(19):1476-82. doi: 10.1016/j.cub.2008.08.013. Epub 2008 Sep 25. Curr Biol. 2008. PMID: 18818082 Free PMC article.
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