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Comment
. 2008 Oct 17;29(4):515-7.
doi: 10.1016/j.immuni.2008.09.009.

Inhibitory receptors signal activation

Wayne M Yokoyama  1
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Free article
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Inhibitory receptors signal activation

Wayne M Yokoyama. Immunity. .
Free article

Abstract

Natural killer cell inhibitory receptors block effector responses by recruiting phosphatases that dephosphorylate molecules involved in activation. However, in this issue of Immunity, Peterson and Long show that inhibitory receptors also signal tyrosine phosphorylation, an event usually indicating cellular activation.

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