Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Sep 15;88(18):8062-6.
doi: 10.1073/pnas.88.18.8062.

Molecular characterization of a region of DNA associated with mutations at the agouti locus in the mouse

S J Bultman  1 , L B Russell, G A Gutierrez-Espeleta, R P Woychik
Affiliations

Molecular characterization of a region of DNA associated with mutations at the agouti locus in the mouse

S J Bultman et al. Proc Natl Acad Sci U S A. .

Abstract

Molecular characterization of a radiation-induced agouti (a)-locus mutation has resulted in the isolation of a segment of DNA that maps at or near the a locus on chromosome 2 in the mouse. This region of DNA is deleted in several radiation- or chemical-induced homozygous-lethal a-locus mutations and is associated with specific DNA structural alterations in two viable a-locus mutations. We propose that DNA probes from this region of chromosome 2 will be useful for ultimately characterizing the individual gene or genes associated with a-locus function.

PubMed Disclaimer

References

    1. J Embryol Exp Morphol. 1976 Feb;35(1):73-80 - PubMed
    1. Proc Natl Acad Sci U S A. 1990 Apr;87(7):2588-92 - PubMed
    1. Nature. 1990 Aug 30;346(6287):850-3 - PubMed
    1. Proc Natl Acad Sci U S A. 1987 May;84(9):2853-7 - PubMed
    1. Genetics. 1989 Apr;121(4):811-8 - PubMed

Publication types

LinkOut - more resources