Comparative Study
doi: 10.1016/0034-5288(91)90025-j.
Antigenic diversity of Cowdria ruminantium isolates determined by cross-immunity
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- PMID: 1896626
- DOI: 10.1016/0034-5288(91)90025-j
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Comparative Study
Antigenic diversity of Cowdria ruminantium isolates determined by cross-immunity
Res Vet Sci.
1991 Jul.
Abstract
Antigenic diversity in five stocks of the tick-borne rickettsia Cowdria ruminantium, the causal agent of heartwater disease of ruminants, was studied by cross-immunity trials in goats and sheep. Complete absence of cross-protection was found only between the Kümm and Kwanyanga stocks, and in all other combinations there were various degrees of cross-immunity. Immunological strain differences were more pronounced in goats than in sheep.
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