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Comparative Study
. 1991 Jul;51(1):24-8.
doi: 10.1016/0034-5288(91)90025-j.

Antigenic diversity of Cowdria ruminantium isolates determined by cross-immunity

F Jongejan  1 , M J Thielemans, C Brière, G Uilenberg
Affiliations
Comparative Study

Antigenic diversity of Cowdria ruminantium isolates determined by cross-immunity

F Jongejan et al. Res Vet Sci. 1991 Jul.

Abstract

Antigenic diversity in five stocks of the tick-borne rickettsia Cowdria ruminantium, the causal agent of heartwater disease of ruminants, was studied by cross-immunity trials in goats and sheep. Complete absence of cross-protection was found only between the Kümm and Kwanyanga stocks, and in all other combinations there were various degrees of cross-immunity. Immunological strain differences were more pronounced in goats than in sheep.

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