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. 1996 Dec;43(12):2123-30.
doi: 10.1016/S0039-9140(96)01999-6.

Spectrophotometric and polarographic investigation of the Ofloxacin-Cu(II) complexes

V Kapetanović, L Milovanović, M Erceg

Spectrophotometric and polarographic investigation of the Ofloxacin-Cu(II) complexes

V Kapetanović et al. Talanta. 1996 Dec.

Abstract

By means of spectrophotometric methods it was found that ofloxacin reacts with copper(II) ions to form complexes with molar ratios of ofloxacin: Cu(II) of 1:1 at pH 4.00, 2:1 at pH 7.02 and 3:1 at pH 8.30. The stability constants of the complexes were determined. The formation of ofloxacin:Cu(II) 1:1 and 3:1 complexes was confirmed by a polarographic method and the corresponding overall stability constant was evaluated.

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