Review
doi: 10.1134/s0006297908090010.
Aconitate hydratase of mammals under oxidative stress
Affiliations
- PMID: 18976211
- PMCID: PMC7087844
- DOI: 10.1134/s0006297908090010
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Review
Aconitate hydratase of mammals under oxidative stress
Biochemistry (Mosc).
2008 Sep.
Abstract
Data on the structure, functions, regulation of activity, and expression of cytosolic and mitochondrial aconitate hydratase isoenzymes of mammals are reviewed. The role of aconitate hydratase and structurally similar iron-regulatory protein in maintenance of homeostasis of cell iron is described. Information on modifications of the aconitate hydratase molecule and changes in expression under oxidative stress is generalized. The role of aconitate hydratase in the pathogenesis of some diseases is considered.
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References
-
- Osipov A. N., Azizova O. A., Vladimirov Yu. A. Uspekhi Biol. Khim. 1990;31:180–208.
-
- Skulachev V. P. Oxygen and Phenomena of Programmed Death. Moscow: Institute of Biomedical Chemistry, Russian Academy of Medical Sciences; 2000.
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