Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Nov;14(11):1809-10.
doi: 10.3201/eid1411.080958.

Widespread oseltamivir resistance in influenza A viruses (H1N1), South Africa

Widespread oseltamivir resistance in influenza A viruses (H1N1), South Africa

Terry G Besselaar et al. Emerg Infect Dis. 2008 Nov.
No abstract available

PubMed Disclaimer

References

    1. Kim CU, Lew W, Williams MA, Liu H, Zhang L, Swaminathan S, et al. Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity. J Am Chem Soc. 1997;119:681–90. 10.1021/ja963036t - DOI - PubMed
    1. Lackenby A, Hungnes O, Dudman SG, Meijer A, Paget WJ, Hay AJ, et al. Emergence of resistance to oseltamivir among influenza A (H1N1) viruses in Europe. Eurosurveillance. 2008;13 [cited 2008 Jul 11]. Available from http://www.eurosurveillance.org/edition/v13n05/080131_2.asp - PubMed
    1. Influenza A. (H1N1) virus resistance to oseltamivir: last quarter 2007 to first quarter 2008. 2008 Jun 13 [cited 2008 Jul 11]. Available from http://www.who.int/csr/disease/influenza/oseltamivir_summary/en/index.html
    1. Besselaar TG, Schoub BD, Blackburn NK. Impact of the introduction of A/Sydney/5/97 H3N2 influenza virus into South Africa. J Med Virol. 1999;59:561–8. 10.1002/(SICI)1096-9071(199912)59:4<561::AID-JMV22>3.0.CO;2-5 - DOI - PubMed
    1. Wetherall NT, Trivedi T, Zeller J, Hodges-Savola C, McKimm-Breschkin JL, Zambon M, et al. Evaluation of neuraminidase enzyme assays using different substrates to measure susceptibility of influenza virus clinical isolates to neuraminidase inhibitors: report of the neuraminidase inhibitor susceptibility network. J Clin Microbiol. 2003;41:742–50. 10.1128/JCM.41.2.742-750.2003 - DOI - PMC - PubMed

Publication types

MeSH terms

LinkOut - more resources