Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2008 Dec;199(6):688.e1-5.
doi: 10.1016/j.ajog.2008.07.029. Epub 2008 Oct 31.

Risk factors for mesh/suture erosion following sacral colpopexy

Geoffrey W Cundiff  1 , Edward Varner, Anthony G Visco, Halina M Zyczynski, Charles W Nager, Peggy A Norton, Joseph Schaffer, Morton B Brown, Linda Brubaker; Pelvic Floor Disorders Network
Affiliations
Randomized Controlled Trial

Risk factors for mesh/suture erosion following sacral colpopexy

Geoffrey W Cundiff et al. Am J Obstet Gynecol. 2008 Dec.

Abstract

Objective: The purpose of this study was to identify risks for mesh/suture erosions following abdominal sacral colpopexy (ASC).

Study design: We analyzed demographic, perioperative variables, and erosion status in 322 participants in the Colpopexy and Urinary Reduction Efforts study 2 years after sacral colpopexy.

Results: The predominant graft used was synthetic mesh: woven polyester (Mersilene; Ethicon, Inc, Somerville, NJ) (42%) or polypropylene (48%). Twenty subjects (6%) experienced mesh/suture erosion. Unadjusted risk factors for mesh/suture erosion were expanded polytrafluroethylene (ePTFE) mesh (ePTFE 4/21 [19%] vs non-ePTFE 16/301 [5%]; odds ratio [OR], 4.2), concurrent hysterectomy (OR, 4.9), and current smoking (OR, 5.2). Of those with mesh erosion, most affected women (13/17) underwent at least 1 surgery for partial or total mesh removal. Two were completely resolved, 6 had persistent problems, and 5 were lost to follow-up. No resolution was documented in the 4 women who elected observation.

Conclusion: Expanded PTFE mesh should not be used for sacral colpopexy. Concurrent hysterectomy and smoking are modifiable risks for mesh/suture erosion.

PubMed Disclaimer

References

    1. Nygaard IE, McCreery R, Brubaker L, Connolly A, Cundiff G, Weber AM, Zyczynski H. Pelvic Floor Disorders Network. Abdominal sacrocolpopexy: a comprehensive review. Obstet Gynecol. 2004;104:805–823. - PubMed
    1. Visco AG, Weidner AC, Barber MD, Myers ER, Cundiff GW, Bump RC, Addison WA. Vaginal mesh erosion after abdominal sacral colpopexy. Am J Obstet Gynecol. 2001;184:297–302. - PubMed
    1. Quiroz LH, Gutman RE, Fagan MJ, Cundiff GW. Partial colpocleisis for the treatment of sacrocolpopexy mesh erosions. Int Urogynecol J Pelvic Floor Dysfunct. 2007 Jul 17; Epub ahead of print. - PubMed
    1. South MM, Foster RT, Webster GD, Weidner AC, Amundsen CL. Surgical excision of eroded mesh after prior abdominal sacrocolpopexy. Am J Obstet Gynecol. 2007 Dec;197(6):615.e1–5. - PubMed
    1. Begley JS, Kupferman SP, Kuznetsov DD, Kobashi KC, Govier FE, McGonigle KF, Muntz HG. Incidence and management of abdominal sacrocolpopexy mesh erosions. Am J Obstet Gynecol. 2005;192:1956–1962. - PubMed

Publication types

MeSH terms