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Review
. 2009 Apr;19(2):89-100.
doi: 10.1016/j.ghir.2008.09.002. Epub 2008 Nov 1.

The aging population--is there a role for endocrine interventions?

Ralf Nass  1 , Gudmundur Johannsson, Jens S Christiansen, John J Kopchick, Michael O Thorner
Affiliations
Review

The aging population--is there a role for endocrine interventions?

Ralf Nass et al. Growth Horm IGF Res. 2009 Apr.

Abstract

The expected increase in the aging population will have a significant impact on society and the health system in the coming years and decades. Enhancing healthspan, "healthy aging", and thus extending the time that the elderly are able to function independently is a significant task and is imperative. Age-dependent changes such as weight loss, sarcopenia and anorexia, which contribute to the development of frailty in the elderly are discussed. The role of the age-dependent decrease in growth hormone secretion in this process and the potential benefits and risks of hormonal interventions to delay, prevent or reverse frailty in the elderly are reviewed.

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