Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Jan;37(Database issue):D1006-12.
doi: 10.1093/nar/gkn838. Epub 2008 Oct 31.

IMGT, the international ImMunoGeneTics information system

Marie-Paule Lefranc  1 , Véronique Giudicelli, Chantal Ginestoux, Joumana Jabado-Michaloud, Géraldine Folch, Fatena Bellahcene, Yan Wu, Elodie Gemrot, Xavier Brochet, Jérôme Lane, Laetitia Regnier, François Ehrenmann, Gérard Lefranc, Patrice Duroux
Affiliations

IMGT, the international ImMunoGeneTics information system

Marie-Paule Lefranc et al. Nucleic Acids Res. 2009 Jan.

Abstract

IMGT, the international ImMunoGeneTics information system (http://www.imgt.org), was created in 1989 by Marie-Paule Lefranc, Laboratoire d'ImmunoGénétique Moléculaire LIGM (Université Montpellier 2 and CNRS) at Montpellier, France, in order to standardize and manage the complexity of immunogenetics data. The building of a unique ontology, IMGT-ONTOLOGY, has made IMGT the global reference in immunogenetics and immunoinformatics. IMGT is a high-quality integrated knowledge resource specialized in the immunoglobulins or antibodies, T cell receptors, major histocompatibility complex, of human and other vertebrate species, proteins of the IgSF and MhcSF, and related proteins of the immune systems of any species. IMGT provides a common access to standardized data from genome, proteome, genetics and 3D structures. IMGT consists of five databases (IMGT/LIGM-DB, IMGT/GENE-DB, IMGT/3Dstructure-DB, etc.), fifteen interactive online tools for sequence, genome and 3D structure analysis, and more than 10,000 HTML pages of synthesis and knowledge. IMGT is used in medical research (autoimmune diseases, infectious diseases, AIDS, leukemias, lymphomas and myelomas), veterinary research, biotechnology related to antibody engineering (phage displays, combinatorial libraries, chimeric, humanized and human antibodies), diagnostics (clonalities, detection and follow-up of residual diseases) and therapeutical approaches (graft, immunotherapy, vaccinology). IMGT is freely available at http://www.imgt.org.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
IMGT®, the international ImMunoGeneTics information system® (http://www.imgt.org). Genomic, genetic and structural components (databases and tools) are in yellow, green and blue, respectively. The IMGT Repertoire and other Web resources are not shown. Interactions in the genomic, genetic and structural approaches are represented with continuous, dotted and broken lines, respectively.
See this image and copyright information in PMC

References

    1. Lefranc M.-P, Lefranc G. The Immunoglobulin FactsBook. London, UK: Academic Press; 2001. pp. 1–458.
    1. Lefranc M.-P, Lefranc G. The T cell receptor FactsBook. London, UK: Academic Press; 2001. pp. 1–398.
    1. Lefranc M.-P, Giudicelli V, Kaas Q, Duprat E, Jabado-Michaloud J, Scaviner D, Ginestoux C, Clément O, Chaume D, Lefranc G. IMGT, the international ImMunoGeneTics information system. Nucleic Acids Res. 2005;33:D593–D597. - PMC - PubMed
    1. Giudicelli V, Lefranc M.-P. Ontology for Immunogenetics: the IMGT-ONTOLOGY. Bioinformatics. 1999;12:1047–1054. - PubMed
    1. Lefranc M.-P. Nomenclature of the human immunoglobulin genes. In: Coligan JE, Bierer BE, Margulies DE, Shevach EM, Strober W, editors. Current Protocols in Immunology. NJ, Hoboken: John Wiley & Sons, Inc.; 2000. pp. A.1P.1–A.1P.37.

Publication types