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Practice Guideline
. 2008 Nov;112(5):1193-4.
doi: 10.1097/AOG.0b013e31818e8793.

ACOG Committee Opinion No. 421, November 2008: antibiotic prophylaxis for infective endocarditis

American College of Obstetricians and Gynecologists Committee on Obstetric Practice
Practice Guideline

ACOG Committee Opinion No. 421, November 2008: antibiotic prophylaxis for infective endocarditis

American College of Obstetricians and Gynecologists Committee on Obstetric Practice. Obstet Gynecol. 2008 Nov.

Abstract

The recommendations for endocarditis prophylaxis from the American Heart Association have changed for three main reasons: 1) most cases of endocarditis are not attributable to an invasive procedure but rather are the result of randomly occurring bacteremia from routine daily activities; 2) prophylaxis may only prevent a small number of cases of infective endocarditis in women undergoing genitourinary procedures; and 3) the risk of antibiotic associated adverse events exceeds the benefit, if any, from prophylactic antibiotic therapy. The specific changes pertinent to the obstetrician-gynecologist are discussed.

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