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. 2008 Nov 4:8:24.
doi: 10.1186/1471-2466-8-24.

The incidence of interstitial lung disease 1995-2005: a Danish nationwide population-based study

Jette B Kornum  1 , Steffen Christensen, Miriam Grijota, Lars Pedersen, Pia Wogelius, Annette Beiderbeck, Henrik Toft Sørensen
Affiliations

The incidence of interstitial lung disease 1995-2005: a Danish nationwide population-based study

Jette B Kornum et al. BMC Pulm Med. .

Abstract

Background: Current data on incidence of interstitial lung diseases (ILDs) are sparse and concerns about an increasing trend have been raised. We examined incidence rates (IRs) of ILDs and changes in IRs between 1995 and 2005.

Methods: All persons with a first-time hospital discharge or outpatient diagnosis of ILD were identified through the Danish National Registry of Patients, which covers all Danish hospitals. Crude and age-standardised IRs were computed for ILD overall, as well as stratified by ILD subcategories.

Results: A total of 21,765 patients with ILD were identified. Between 1995 and 1998 the overall standardised IR of ILD decreased from 27.14 (95% CI 25.82-28.46) per 100,000 person-years to 19.36 (95% CI 18.26-20.46) per 100,000 person-years. After 1998 the IR increased considerably, peaking at 34.34 (95% CI 32.84-35.85) per 100,000 person-years in 2002. Subsequently there was a slight decrease. The highest IR was observed in the non-specific category "Respiratory disorders in diseases classified elsewhere". By ILD subcategory, the greatest average increase during the study period was observed in "Respiratory disorders in diseases classified elsewhere".

Conclusion: The incidence rate of ILD in Denmark increased during the study period, most pronounced for ILDs associated with systemic diseases.

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Figures

Figure 1
Figure 1
Standardised incidence rates of ILD overall and by gender. Denmark 1995–2005. Age-standardised to the 2000 world population.
See this image and copyright information in PMC

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