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Comment
. 2008 Nov 6;3(5):465-6.
doi: 10.1016/j.stem.2008.10.011.

Develop-WNTs in somatic cell reprogramming

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Develop-WNTs in somatic cell reprogramming

Bradley J Merrill. Cell Stem Cell. .
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Abstract

Two manuscripts published recently in Cell Stem Cell (Lluis et al., 2008 [this issue]; Marson et al., 2008) show that Wnt-beta-catenin signaling stimulates nuclear reprogramming. These two studies, using distinct reprogramming methods, offer insights into the mechanisms underlying acquisition and maintenance of pluripotency.

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