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Review
. 2008 Nov 6;3(5):480-3.
doi: 10.1016/j.stem.2008.10.007.

Heterogeneity of embryonic and adult stem cells

Thomas Graf  1 , Matthias Stadtfeld
Affiliations
Free article
Review

Heterogeneity of embryonic and adult stem cells

Thomas Graf et al. Cell Stem Cell. .
Free article

Abstract

New studies suggest that stem cells of embryonic, neural, and hematopoietic origin are heterogeneous, with cells moving between two or more metastable states. These cell states show a bias in their differentiation potential and correlate with specific patterns of transcription factor expression and chromatin modifications.

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