Myosin learns to recruit AMPA receptors
- PMID: 18984153
- DOI: 10.1016/j.cell.2008.10.013
Myosin learns to recruit AMPA receptors
Abstract
The induction of long-term potentiation (LTP) leads to an increase in the density of AMPA receptors at dendritic spines. New work by Wang et al. (2008) reveals the mechanism by which myosin Vb regulates the intracellular trafficking of AMPA receptors from recycling endosomes to synaptic sites during LTP.
Comment on
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Myosin Vb mobilizes recycling endosomes and AMPA receptors for postsynaptic plasticity.Cell. 2008 Oct 31;135(3):535-48. doi: 10.1016/j.cell.2008.09.057. Cell. 2008. PMID: 18984164 Free PMC article.
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