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Review
. 2008 Oct 31;135(3):417-20.
doi: 10.1016/j.cell.2008.10.007.

Knockdown screens to knockout HIV-1

Stephen P Goff  1
Affiliations
Review

Knockdown screens to knockout HIV-1

Stephen P Goff. Cell. .

Abstract

Three recent screens use siRNAs to identify host genes that are critical for HIV-1 replication. These screens have uncovered hundreds of human genes not previously known to be commandeered by the virus during infection. Although some caveats remain, this screening approach opens up a new landscape of viral-host interactions for future exploration.

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