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Comment
. 2008 Nov 7;322(5903):857; author reply 857.
doi: 10.1126/science.1158565.

Comment on "Whole-genome shotgun sequencing of mitochondria from ancient hair shafts"

Regis Debruyne  1 , Carsten Schwarz, Hendrik Poinar
Affiliations
Comment

Comment on "Whole-genome shotgun sequencing of mitochondria from ancient hair shafts"

Regis Debruyne et al. Science. .

Abstract

Gilbert et al. (Reports, 28 September 2007, p. 1927) reported that "hair shafts surpass comparably stored bone as an aDNA source [...] in regard to preservation and concentration of mtDNA." When experimental parameters are carefully controlled for, including adequate sampling, quantitative polymerase chain reaction analysis, and modeling the decay of DNA, the general importance of this claim is not supported.

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Comment on

  • Whole-genome shotgun sequencing of mitochondria from ancient hair shafts.
    Gilbert MT, Tomsho LP, Rendulic S, Packard M, Drautz DI, Sher A, Tikhonov A, Dalén L, Kuznetsova T, Kosintsev P, Campos PF, Higham T, Collins MJ, Wilson AS, Shidlovskiy F, Buigues B, Ericson PG, Germonpré M, Götherström A, Iacumin P, Nikolaev V, Nowak-Kemp M, Willerslev E, Knight JR, Irzyk GP, Perbost CS, Fredrikson KM, Harkins TT, Sheridan S, Miller W, Schuster SC. Gilbert MT, et al. Science. 2007 Sep 28;317(5846):1927-30. doi: 10.1126/science.1146971. Science. 2007. PMID: 17901335

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