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Comment
. 2008 Nov 15;112(10):3921-2.
doi: 10.1182/blood-2008-09-176685.

WASp stings mature lymphocytes

Affiliations
Comment

WASp stings mature lymphocytes

Eva Severinson. Blood. .

Abstract

WAS is an X-linked immunodeficiency disease caused by mutations in WASp. Meyer-Bahlburg and colleagues and Westerberg and colleagues in this issue of Blood have investigated lymphocyte subpopulations in WASp+/- mice and found that WASp confers a selective advantage to the most mature T and B cells.

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Conflict of interest statement

Conflict-of-interest disclosure: The author declares no competing financial interests. ■

Figures

None
Differentiation of B cells. CLP indicates common lymphoid progenitor. WASp is most important in the more mature B-cell subpopulations.

Comment on

References

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