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Review
. 2008 Nov;8(13):1395-406.
doi: 10.2174/138955708786369582.

Antioxidant therapy in Alzheimer's disease: theory and practice

Gjumrakch Aliev  1 , Mark E Obrenovich, V Prakash Reddy, Justin C Shenk, Paula I Moreira, Akihiko Nunomura, Xiongwei Zhu, Mark A Smith, George Perry
Affiliations
Review

Antioxidant therapy in Alzheimer's disease: theory and practice

Gjumrakch Aliev et al. Mini Rev Med Chem. 2008 Nov.

Abstract

Alzheimer disease treatment has yet to yield a successful therapy that addresses the source of the damage found in brains. Of the varied proposed theories of AD etiology, reactive oxygen species (ROS) generation is cited as a common factor. Efforts to reduce the pathology associated with ROS via antioxidants therefore offer new hope to patients suffering from this devastative disease.

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