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Case Reports
. 2009 Aug;13(5):632-5.
doi: 10.1111/j.1399-3046.2008.01027.x. Epub 2008 Oct 7.

Urinary excretion of ganciclovir contributes to improvement of adenovirus-associated hemorrhagic cystitis after allogeneic bone marrow transplantation

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Case Reports

Urinary excretion of ganciclovir contributes to improvement of adenovirus-associated hemorrhagic cystitis after allogeneic bone marrow transplantation

Yozo Nakazawa et al. Pediatr Transplant. 2009 Aug.

Abstract

A nine-yr-old girl developed AdV-associated HC after bone marrow transplantation. Intravenous GCV markedly reduced urinary AdV DNA loads and improved clinical findings. This appeared to result partly from a high concentration of GCV in urine. GCV may be effective for AdV-induced HC without definitive disseminated infection.

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