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. 2008 Jul-Sep;57(3):131-7.

Romanian anti-TB drugs resistance surveillance 2003-2004

Ioan Paul Stoicescu  1 , Daniela Homorodean, Domnica Chiotan, Olga Moldovan, Daniela Diculencu, Cristian Popa, Anca Macri, Iuliana Husar, Lucica Diţiu, Mohamed Abdel Aziz, Sven Hoffner
Affiliations
  • PMID: 18998325

Romanian anti-TB drugs resistance surveillance 2003-2004

Ioan Paul Stoicescu et al. Pneumologia. 2008 Jul-Sep.

Abstract

Romania decided and initiated a DRS for anti-TB drugs at national level using the standardized methodology proposed by WHO and IUATLD. The DRS protocol was designed with technical assistance from WHO; the surveillance started in June 2003 and ended in June 2004. It was tested the susceptibility to the 4 first line anti-TB drugs: Isoniazide (H), Rifampicin (R), Streptomycin (S), Ethambutol (E). Drug susceptibility testing used: indirect absolute concentration method. There were included in the survey 1251 TB patients from the 60 clusters: 869 new cases and 382 previously treated. From the penitentiary system were included 85 TB patients, 47 new cases and 38 previously treated.

Results: [table: see text]. Estimations of the trend of anti-TB drug resistance in Romania for the next period was proposed.

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