Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2008 Nov-Dec;22(6):1427-31.
doi: 10.1111/j.1939-1676.2008.0203.x.

Congenital thyroid hypoplasia and seizures in 2 littermate kittens

A M Traas  1 , B L Abbott, A French, U Giger
Affiliations
Case Reports

Congenital thyroid hypoplasia and seizures in 2 littermate kittens

A M Traas et al. J Vet Intern Med. 2008 Nov-Dec.

Erratum in

  • J Vet Intern Med. 2009 Jan-Feb;23(1):225
No abstract available

PubMed Disclaimer

Figures

Fig 1
Fig 1
Photographs of affected littermate kittens. Kitten A (photos A and B) and Kitten B (photos C and D) at 14 weeks of age. Note the disproportionate dwarfism typical of cretinism.
Fig 2
Fig 2
Radiographs of Kitten A at 14 weeks of age. Note the wide growth plates with delayed ossification. Vertebral bodies (photos A and D) are widened and square. Carpal (photo C) and tarsal (photo D) bones also have delayed ossification. Megacolon (A,D) and a fracture of a sternebrae through the growth plate (D) can also be seen.
Fig 3
Fig 3
Gross pathology of Kitten B cervical region. On postmortem examination severely hypoplastic thyroid glands were paper-thin, pale brown, and indistinct from surrounding tissues (arrow).
Fig 4
Fig 4
Histopathology of normal and affected thyroid glands. Histology at 2 different magnifications, showing a normal age-matched thyroid gland (A, C) compared with an affected thyroid gland (B, D). Follicles in the affected glands are decreased in both density and size.
See this image and copyright information in PMC

References

    1. Jones BR, Gruffydd-Jones TJ, Sparkes AH, Lucke VM. Preliminary studies on congenital hypothyroidism in a family of Abyssinian cats. Vet Rec. 1992;131:145–148. - PubMed
    1. Sjollema BE, den Hartog MT, de Vijlder JJ, et al. Congenital hypothyroidism in two cats due to defective organification: Data suggesting loosely anchored thyroperoxidase. Acta Endocrinol (Copenhagen) 1991;125:435–440. - PubMed
    1. Tanase H, Kudo K, Horikoshi H, et al. Inherited primary hypothyroidism with thyrotrophin resistance in Japanese cats. J Endocrinol. 1991;129:245–251. - PubMed
    1. Firth MF, Fondacaro JV, Greco DS. Challenging cases in internal medicine: What’s your diagnosis? Vet Med. 2000;95:606–614.
    1. Szabo SD, Wells KL. What is your diagnosis? Congenital hypothyroidism. J Am Vet Med Assoc. 2007;230:29–30. - PubMed

Publication types

LinkOut - more resources