Asmparts: assembly of biological model parts
- PMID: 19003441
- PMCID: PMC2553328
- DOI: 10.1007/s11693-008-9013-4
Asmparts: assembly of biological model parts
Abstract
We propose a new computational tool to produce models of biological systems by assembling models from biological parts. Our software not only takes advantage of modularity, but it also enforces standardisation in part characterisation by considering a model of each part. We have used model parts in SBML to design transcriptional networks. Our software is open source, it works in linux and windows platforms, and it could be used to automatically produce models in a server. Our tool not only facilitates model design, but it will also help to promote the establishment of a registry of model parts.
Figures
References
-
- {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1038/446497a', 'is_inner': False, 'url': 'https://doi.org/10.1038/446497a'}, {'type': 'PubMed', 'value': '17392770', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/17392770/'}]}
- Alon U (2007) Simplicity in biology. Nature 446:497 - PubMed
-
- {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1016/S0092-8674(03)00346-5', 'is_inner': False, 'url': 'https://doi.org/10.1016/s0092-8674(03)00346-5'}, {'type': 'PubMed', 'value': '12787501', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/12787501/'}]}
- Atkinson MR, Savageau MA, Myers JT, Ninfa AJ (2003) Development of genetic circuitry exhibiting toggle switch or oscillatory behavior in Escherichia coli. Cell 113:597–607 - PubMed
-
- {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1038/43072', 'is_inner': False, 'url': 'https://doi.org/10.1038/43072'}]}
- Barkai N, Leibler S (1997) Robustness in simple biochemical networks. Nature 387:855–857
-
- Bornstein BJ et al (2007) libSBML. http://sbml.org/software/libsbml
-
- {'text': '', 'ref_index': 1, 'ids': [{'type': 'PMC', 'value': 'PMC2132448', 'is_inner': False, 'url': 'https://pmc.ncbi.nlm.nih.gov/articles/PMC2132448/'}, {'type': 'PubMed', 'value': '18004278', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/18004278/'}]}
- Cox RS III, Surette MG, Elowitz MB (2007) Programming gene expression with combinatorial promoters. Mol Syst Biol 3:145 - PMC - PubMed
LinkOut - more resources
Full Text Sources
