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. 2007 Mar;1(1):71-84.
doi: 10.1007/s11571-006-9007-4. Epub 2006 Oct 31.

The influences of task difficulty and response correctness on neural systems supporting fluid reasoning

M Layne Kalbfleisch  1 , John W Van Meter, Thomas A Zeffiro
Affiliations

The influences of task difficulty and response correctness on neural systems supporting fluid reasoning

M Layne Kalbfleisch et al. Cogn Neurodyn. 2007 Mar.

Abstract

This functional magnetic resonance imaging (fMRI) study examined neural contributions to managing task difficulty and response correctness during fluid reasoning. Previous studies investigate reasoning by independently varying visual complexity or task difficulty, or the specific domain. Under natural conditions these factors interact in a complex manner to support dynamic combinations of perceptual and conceptual processes. This study investigated fluid reasoning under circumstances that would represent the cognitive flexibility of real life decision-making. Results from a mixed effects analysis corrected for multiple comparisons indicate involvement of cortical and subcortical areas during fluid reasoning. A 2 x 2 ANOVA illustrates activity related to variances in task difficulty correlated with increased blood oxygenation level-dependent (BOLD)-signal in the left middle frontal gyrus (BA6). Activity related to response correctness correlated with increased BOLD-signal in a larger, distributed system including right middle frontal gyrus (BA6), right superior parietal lobule (BA7), left inferior parietal lobule (BA40), left lingual gyrus (BA19), and left cerebellum (Lobule VI). The dissociation of function in left BA 6 for task difficulty and right BA6 for response correctness and the involvement of a more diffuse network involving the left cerebellum in response correctness extends knowledge about contributions of classic motor and premotor areas supporting higher level cognition.

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References

    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1126/science.275.5308.1940', 'is_inner': False, 'url': 'https://doi.org/10.1126/science.275.5308.1940'}, {'type': 'PubMed', 'value': '9072973', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/9072973/'}]}
    2. Allen G, Buxton RB, Wong EC, Courchesne E (1997) Attentional activation of the cerebellum independent of motor involvement. Science 275:1940–1943 - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'PMC', 'value': 'PMC6758676', 'is_inner': False, 'url': 'https://pmc.ncbi.nlm.nih.gov/articles/PMC6758676/'}, {'type': 'PubMed', 'value': '11784801', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/11784801/'}]}
    2. Bischoff-Grethe A, Ivry RB, Grafton ST (2002) Cerebellar involvement in response reassignment rather than attention. J Neurosci 22:546–553 - PMC - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1016/j.cogbrainres.2003.12.009', 'is_inner': False, 'url': 'https://doi.org/10.1016/j.cogbrainres.2003.12.009'}, {'type': 'PubMed', 'value': '15130588', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/15130588/'}]}
    2. Blackwood N, Ffytche D, Simmons A, Bentall R, Murray R, Howard R (2004) The cerebellum and decision making under uncertainty. Brain Res Cogn Brain Res 20:46–53 - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1007/s00221-003-1597-z', 'is_inner': False, 'url': 'https://doi.org/10.1007/s00221-003-1597-z'}, {'type': 'PubMed', 'value': '12955381', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/12955381/'}]}
    2. Blakemore SJ, Sirigu A (2003) Action prediction in the cerebellum and in the parietal lobe. Exp Brain Res 153:239–245 - PubMed
    1. Brett M (1999) The MNI Brain and the Talairach Atlas