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. 2008 Sep-Oct;10(9-10):999-1002.
doi: 10.1080/10286020802240418.

Synthesis and enantiomeric resolution of (+/-)-pinocembrin

Yue Yuan  1 , Qing-Yun Yang, Yuan-Feng Tong, Feng Chen, Yan Qi, Ya-Bo Duan, Song Wu
Affiliations

Synthesis and enantiomeric resolution of (+/-)-pinocembrin

Yue Yuan et al. J Asian Nat Prod Res. 2008 Sep-Oct.

Abstract

A convenient method for the synthesis and enantiomeric resolution of ( +/- )-pinocembrin has been developed. This route involves the hydrogenation of 5,7-dihydroxyflavone, the derivatization of racemic pinocembrin with chiral amine, and the separation of the diastereoisomers due to their different physical properties.

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