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Review
. 2008 Oct;95(10):979-83.
doi: 10.1684/bdc.2008.0732.

[Methodological aspects on new protocols in oncology]

[Article in French]
Elisabeth Luporsi  1
Affiliations
Review

[Methodological aspects on new protocols in oncology]

[Article in French]
Elisabeth Luporsi. Bull Cancer. 2008 Oct.

Abstract

This review will summarize specific methodological aspects in targeted therapies like EPR (early progression rate) or RDD (randomized discontinuation design), along with Adaptive Design such as CRM (continual reassessment method, Eff-TOX (dose-finding based on efficacy-toxicity, PPD (predictive probability design) or ADTT (adaptive randomization for targeted therapy) methods.

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