Pol V transcribes to silence
- PMID: 19013268
- DOI: 10.1016/j.cell.2008.10.027
Pol V transcribes to silence
Abstract
In most cases, the functions of long noncoding RNAs remain uncertain. Working in the model plant Arabidopsis, Wierzbicki et al. (2008) provide evidence that transcription of intergenic noncoding regions by RNA polymerase V promotes heterochromatin formation and silencing of nearby genes.
Comment on
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Noncoding transcription by RNA polymerase Pol IVb/Pol V mediates transcriptional silencing of overlapping and adjacent genes.Cell. 2008 Nov 14;135(4):635-48. doi: 10.1016/j.cell.2008.09.035. Cell. 2008. PMID: 19013275 Free PMC article.
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