Unlocking CNS cell type heterogeneity
- PMID: 19013270
- DOI: 10.1016/j.cell.2008.10.031
Unlocking CNS cell type heterogeneity
Abstract
A major challenge to understanding how cells work together in the central nervous system (CNS) is the heterogeneous cellular composition of the brain. In this issue, Heiman et al. (2008) and Doyle et al. (2008) introduce a new strategy (TRAP) that enables the profiling of translated mRNAs in specific CNS cell populations without the need for purifying cells to homogeneity.
Comment on
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A translational profiling approach for the molecular characterization of CNS cell types.Cell. 2008 Nov 14;135(4):738-48. doi: 10.1016/j.cell.2008.10.028. Cell. 2008. PMID: 19013281 Free PMC article.
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Application of a translational profiling approach for the comparative analysis of CNS cell types.Cell. 2008 Nov 14;135(4):749-62. doi: 10.1016/j.cell.2008.10.029. Cell. 2008. PMID: 19013282 Free PMC article.
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