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Comparative Study
. 2008 Oct;49(10):1069-78.
doi: 10.1111/j.1469-7610.2008.02000.x.

The effects of pre- and postnatal depression in fathers: a natural experiment comparing the effects of exposure to depression on offspring

Paul G Ramchandani  1 , Thomas G O'Connor, Jonathan Evans, Jon Heron, Lynne Murray, Alan Stein
Affiliations
Free PMC article
Comparative Study

The effects of pre- and postnatal depression in fathers: a natural experiment comparing the effects of exposure to depression on offspring

Paul G Ramchandani et al. J Child Psychol Psychiatry. 2008 Oct.
Free PMC article

Abstract

Background: Depression in fathers in the postnatal period is associated with an increased risk of behavioural problems in their offspring, particularly for boys. The aim of this study was to examine for differential effects of depression in fathers on children's subsequent psychological functioning via a natural experiment comparing prenatal and postnatal exposure.

Methods: In a longitudinal population cohort study (the Avon Longitudinal Study of Parents and Children (ALSPAC)) we examined the associations between depression in fathers measured in the prenatal and postnatal period (measured using the Edinburgh Postnatal Depression Scale), and later behavioural/emotional and psychiatric problems in their children, assessed at ages 3(1/2) and 7 years.

Results: Children whose fathers were depressed in both the prenatal and postnatal periods had the highest risks of subsequent psychopathology, measured by total problems at age 3(1/2) years (Odds Ratio 3.55; 95% confidence interval 2.07, 6.08) and psychiatric diagnosis at age 7 years (OR 2.54; 1.19, 5.41). Few differences emerged when prenatal and postnatal depression exposure were directly compared, but when compared to fathers who were not depressed, boys whose fathers had postnatal depression only had higher rates of conduct problems aged 3(1/2) years (OR 2.14; 1.22, 3.72) whereas sons of the prenatal group did not (OR 1.41; .75, 2.65). These associations changed little when controlling for maternal depression and other potential confounding factors.

Conclusions: The findings of this study suggest that the increased risk of later conduct problems, seen particularly in the sons of depressed fathers, maybe partly mediated through environmental means. In addition, children whose fathers are more chronically depressed appear to be at a higher risk of emotional and behavioural problems. Efforts to identify the precise mechanisms by which transmission of risk may occur should be encouraged to enable the development of focused interventions to mitigate risks for young children.

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Figures

Figure 1
Figure 1
Comparison of conduct and total problems at age 3 years in the three depressed groups compared to the non-depressed group.
Figure 2
Figure 2
Comparison of conduct and total problems (age 3) and psychiatric diagnoses (age 7) in the three depressed groups compared to the non-depressed group.
See this image and copyright information in PMC

References

    1. Cabrera NJ, Tamis-LeMonda CS, Bradley RH, Hofferth S, Lamb ME. Fatherhood in the twenty-first century. Child Development. 2000;71:127–136. - PubMed
    1. Carro M, Grant K, Gotlib I, Compas B. Postpartum depression and child development: An investigation of mothers and fathers as sources of risk and resilience. Development and Psychopathology. 1993;5:567–579.
    1. Cassano M, Adrian M, Veits G, Zeman J. The inclusion of fathers in the empirical investigation of child psychopathology: An update. Journal of Clinical Child and Adolescent Psychology. 2006;35:583–589. - PubMed
    1. Collishaw S, Dunn J, O'Connor TG, Golding J. Maternal childhood abuse and offspring adjustment over time. Developmental Psychopathology. 2007;19:367–383. - PubMed
    1. Cox JL, Holden JM, Sagovsky R. Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. British Journal of Psychiatry. 1987;150:782–786. - PubMed

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