Case Reports
doi: 10.1016/j.diagmicrobio.2008.09.008.
Epub 2008 Nov 21.
Interlaboratory discrepancy of antigenuria results in 2 patients with AIDS and histoplasmosis
Affiliations
- PMID: 19026512
- DOI: 10.1016/j.diagmicrobio.2008.09.008
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Case Reports
Interlaboratory discrepancy of antigenuria results in 2 patients with AIDS and histoplasmosis
Diagn Microbiol Infect Dis.
2009 Jan.
Abstract
Histoplasma polysaccharide antigen testing is used routinely to diagnose histoplasmosis. At least 3 antigen tests are commercially available. Controversy exists about the relative accuracy of these tests. We report 2 patients with AIDS and culture-confirmed Histoplasma capsulatum meningitis from whom discrepant Histoplasma polysaccharide antigen results were obtained from different laboratories and discuss the potential clinical implications of these results.
Comment in
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Extent of interlaboratory discrepancies for polyclonal Histoplasma antigen enzyme immunoassay cannot be determined without a large split-sample study.Diagn Microbiol Infect Dis. 2010 Feb;66(2):233-4. doi: 10.1016/j.diagmicrobio.2009.09.018. Epub 2009 Nov 6. Diagn Microbiol Infect Dis. 2010. PMID: 19896791 No abstract available.
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