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Case Reports
. 2009 Jan;63(1):111-4.
doi: 10.1016/j.diagmicrobio.2008.09.008. Epub 2008 Nov 21.

Interlaboratory discrepancy of antigenuria results in 2 patients with AIDS and histoplasmosis

David S McKinsey  1 , Joel P McKinsey, Noelle Northcutt, Juan C Sarria
Affiliations
Case Reports

Interlaboratory discrepancy of antigenuria results in 2 patients with AIDS and histoplasmosis

David S McKinsey et al. Diagn Microbiol Infect Dis. 2009 Jan.

Abstract

Histoplasma polysaccharide antigen testing is used routinely to diagnose histoplasmosis. At least 3 antigen tests are commercially available. Controversy exists about the relative accuracy of these tests. We report 2 patients with AIDS and culture-confirmed Histoplasma capsulatum meningitis from whom discrepant Histoplasma polysaccharide antigen results were obtained from different laboratories and discuss the potential clinical implications of these results.

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