Bag-in-the-lens: first pathological analysis of a human eye obtained postmortem

Abstract

We analyzed an enucleated eye obtained postmortem from an 86-year-old donor who had been implanted with a hydrophilic acrylic bag-in-the-lens 4 months earlier. To our knowledge, this is the first donor eye implanted with this design to undergo pathological analysis. High-frequency ultrasound showed a well-centered IOL, fixated at the level of the capsular bag. Gross and light microscopic analyses of the eye showed that if anterior and posterior capsule openings are well stretched around the optic of this IOL design, proliferative/regenerative material is potentially confined to the intercapsular space of the capsular bag remnant outside the optic rim.