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Case Reports
. 2008 Nov 14;14(42):6572-4.
doi: 10.3748/wjg.14.6572.

Albumin liver dialysis as pregnancy-saving procedure in cholestatic liver disease and intractable pruritus

Maud Lemoine  1 , Aurelie Revaux, Claire Francoz, Guillaume Ducarme, Sabine Brechignac, Emmanuel Jacquemin, Michele Uzan, Nathalie Ganne-Carrie
Affiliations
Case Reports

Albumin liver dialysis as pregnancy-saving procedure in cholestatic liver disease and intractable pruritus

Maud Lemoine et al. World J Gastroenterol. .

Abstract

Progressive familial intrahepatic cholestasis type 3 (PFIC3) is a rare cholestatic liver disease. Such liver disease can get worse by female hormone disorder. Albumin dialysis or Molecular Adsorbent Recirculating System (MARS) has been reported to reverse severe cholestasis-linked pruritus. Here, we report the first use of MARS during a spontaneous pregnancy and its successful outcome in a patient with PFIC3 and intractable pruritus. Albumin dialysis could be considered as a pregnancy-saving procedure in pregnant women with severe cholestasis and refractory pruritus.

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Figures

Figure 1
Figure 1
Course of total Bile Acids during the pregnancy. P: Plasmapheresis; M: MARS: Molecular Adsorbent Recirculating System; CS: Caesarean section.
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