Review
doi: 10.1016/j.neuron.2008.11.008.
Biological functions of activity-dependent transcription revealed
Affiliations
- PMID: 19038208
- DOI: 10.1016/j.neuron.2008.11.008
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Review
Biological functions of activity-dependent transcription revealed
Neuron.
.
Free article
Abstract
Neuronal activity regulates the transcription of a large set of genes, many of which encode proteins that modify synaptic function. In this issue of Neuron, Hong et al. selectively impair activity-dependent Bdnf transcription and demonstrate that this process is required for inhibitory synapse development.
Comment on
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A biological function for the neuronal activity-dependent component of Bdnf transcription in the development of cortical inhibition.Neuron. 2008 Nov 26;60(4):610-24. doi: 10.1016/j.neuron.2008.09.024. Neuron. 2008. PMID: 19038219 Free PMC article.
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