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Review
. 2008 Dec;43(12):e25-9.
doi: 10.1016/j.jpedsurg.2008.09.017.

Absence of the interstitial cells of Cajal in a child with chronic pseudoobstruction

Marie-Chantal Struijs  1 , Ivan R Diamond, Paul B Pencharz, Kenneth T E Chang, Sandra Viero, Jacob C Langer, Paul W Wales
Affiliations
Review

Absence of the interstitial cells of Cajal in a child with chronic pseudoobstruction

Marie-Chantal Struijs et al. J Pediatr Surg. 2008 Dec.

Abstract

Absence or altered distribution of the interstitial cells of Cajal (ICCs) has been described in association with intestinal pseudoobstruction in adults. We report the first pediatric case with regional absence of ICCs in the distal small bowel and colon associated with intestinal pseudoobstruction. This report highlights that abnormalities of the ICCs in intestinal pseudoobstruction should be considered early in the diagnostic workup of children with intestinal pseudoobstruction.

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