Organizing junctions at the cell-cell interface
- PMID: 19041742
- DOI: 10.1016/j.cell.2008.11.002
Organizing junctions at the cell-cell interface
Abstract
The zonula adherens (ZA) is a specialized cadherin-based structure found at the contacts between epithelial cells. Meng et al. (2008) now identify a protein complex containing the microtubule minus-end-binding protein Nezha, which provides a critical link between microtubules and cadherins in ZA biogenesis and maintenance.
Comment on
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Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts.Cell. 2008 Nov 28;135(5):948-59. doi: 10.1016/j.cell.2008.09.040. Cell. 2008. PMID: 19041755
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